2021 Conference USA Leaders Passing Defense - Games in November Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 4 | 111 | 57 | 51.4 | 774 | 7.0 | 3 | 7 | 106.23 | 27.8 | 193.5 |
| 2 | North Texas | 4 | 114 | 60 | 52.6 | 737 | 6.5 | 4 | 2 | 115.01 | 28.5 | 184.3 |
| 3 | UTSA | 4 | 76 | 42 | 55.3 | 669 | 8.8 | 5 | 2 | 145.66 | 19.0 | 167.3 |
| 4 | Western Kentucky | 4 | 178 | 106 | 59.6 | 1081 | 6.1 | 6 | 14 | 105.95 | 44.5 | 270.3 |
| 5 | UTEP | 4 | 126 | 71 | 56.3 | 864 | 6.9 | 7 | 1 | 130.69 | 31.5 | 216.0 |
| 5 | Old Dominion | 4 | 151 | 94 | 62.3 | 1105 | 7.3 | 7 | 4 | 133.72 | 37.8 | 276.3 |
| 5 | Charlotte | 4 | 116 | 78 | 67.2 | 1172 | 10.1 | 7 | 4 | 165.12 | 29.0 | 293.0 |
| 8 | Florida International | 4 | 92 | 58 | 63.0 | 791 | 8.6 | 8 | 2 | 159.61 | 23.0 | 197.8 |
| 8 | Middle Tennessee | 4 | 146 | 87 | 59.6 | 938 | 6.4 | 8 | 3 | 127.53 | 36.5 | 234.5 |
| 8 | UAB | 4 | 144 | 88 | 61.1 | 955 | 6.6 | 8 | 2 | 132.37 | 36.0 | 238.8 |
| 8 | Louisiana Tech | 4 | 101 | 61 | 60.4 | 986 | 9.8 | 8 | 4 | 160.62 | 25.3 | 246.5 |
| 12 | Marshall | 4 | 138 | 78 | 56.5 | 1012 | 7.3 | 9 | 1 | 138.19 | 34.5 | 253.0 |
| 12 | Florida Atlantic | 4 | 162 | 113 | 69.8 | 1323 | 8.2 | 9 | 3 | 152.98 | 40.5 | 330.8 |
| 14 | Rice | 4 | 148 | 98 | 66.2 | 1456 | 9.8 | 13 | 6 | 169.74 | 37.0 | 364.0 |