2021 Conference USA Leaders Tackles For Loss - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Marshall | 1 | 12.0 | 37 | 12.00 |
| 2 | Rice | 2 | 9.0 | 45 | 4.50 |
| 3 | UAB | 2 | 8.0 | 37 | 4.00 |
| 4 | Old Dominion | 1 | 6.0 | 18 | 6.00 |
| 5 | Southern Mississippi | 1 | 4.0 | 17 | 4.00 |
| 5 | Western Kentucky | 1 | 4.0 | 14 | 4.00 |
| 5 | UTSA | 1 | 4.0 | 11 | 4.00 |
| 8 | Louisiana Tech | 1 | 3.0 | 11 | 3.00 |