2021 Conference USA Leaders Tackles For Loss - Games in October Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Middle Tennessee | 4 | 36.0 | 150 | 9.00 |
| 2 | UTEP | 4 | 33.0 | 142 | 8.25 |
| 2 | UAB | 4 | 33.0 | 126 | 8.25 |
| 4 | UTSA | 4 | 30.0 | 161 | 7.50 |
| 5 | Western Kentucky | 5 | 29.0 | 128 | 5.80 |
| 6 | North Texas | 4 | 26.0 | 116 | 6.50 |
| 7 | Florida Atlantic | 4 | 24.0 | 90 | 6.00 |
| 8 | Marshall | 4 | 22.0 | 94 | 5.50 |
| 8 | Rice | 4 | 22.0 | 85 | 5.50 |
| 10 | Old Dominion | 4 | 20.0 | 68 | 5.00 |
| 10 | Southern Mississippi | 4 | 20.0 | 67 | 5.00 |
| 12 | Charlotte | 4 | 19.0 | 78 | 4.75 |
| 12 | Louisiana Tech | 4 | 19.0 | 60 | 4.75 |
| 14 | Florida International | 4 | 18.0 | 44 | 4.50 |