2021 Big 12 Conference Leaders Opponent Penalties - Games Won Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Kansas | 2 | 18 | 137 | 9.0 | 68.5 |
| 2 | Oklahoma State | 12 | 81 | 638 | 6.8 | 53.2 |
| 3 | Oklahoma | 11 | 69 | 555 | 6.3 | 50.5 |
| 4 | Texas Tech | 7 | 40 | 313 | 5.7 | 44.7 |
| 5 | Texas | 5 | 26 | 218 | 5.2 | 43.6 |
| 6 | Kansas State | 8 | 42 | 328 | 5.3 | 41.0 |
| 6 | TCU | 5 | 24 | 205 | 4.8 | 41.0 |
| 8 | Baylor | 12 | 53 | 456 | 4.4 | 38.0 |
| 9 | Iowa State | 7 | 35 | 265 | 5.0 | 37.9 |
| 10 | West Virginia | 6 | 29 | 225 | 4.8 | 37.5 |