2021 Big 12 Conference Leaders Sacks - Games in November Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Oklahoma State | 4 | 26.0 | 167 | 6.50 |
| 2 | Iowa State | 4 | 15.0 | 103 | 3.75 |
| 3 | Baylor | 4 | 13.0 | 78 | 3.25 |
| 4 | Oklahoma | 3 | 9.0 | 70 | 3.00 |
| 5 | Kansas | 4 | 8.0 | 65 | 2.00 |
| 5 | Kansas State | 4 | 8.0 | 49 | 2.00 |
| 7 | Texas | 4 | 6.0 | 28 | 1.50 |
| 8 | West Virginia | 4 | 5.0 | 36 | 1.25 |
| 9 | TCU | 4 | 4.0 | 30 | 1.00 |
| 10 | Texas Tech | 3 | 2.0 | 7 | 0.67 |