2021 Big 12 Conference Leaders Interceptions - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Baylor | 13 | 19 | 254 | 2 | 1.46 |
| 2 | Oklahoma State | 13 | 9 | 159 | 1 | 0.69 |
| 3 | Kansas | 11 | 7 | 146 | 2 | 0.64 |
| 4 | Kansas State | 12 | 10 | 108 | 0 | 0.83 |
| 5 | West Virginia | 12 | 9 | 104 | 0 | 0.75 |
| 6 | Texas Tech | 12 | 10 | 100 | 2 | 0.83 |
| 7 | Texas | 12 | 7 | 91 | 1 | 0.58 |
| 8 | TCU | 11 | 9 | 83 | 1 | 0.82 |
| 9 | Oklahoma | 12 | 10 | 67 | 0 | 0.83 |
| 10 | Iowa State | 12 | 9 | 63 | 1 | 0.75 |