2021 Atlantic Coast Conference Leaders First Downs - Games at Home Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 7 | 68 | 119 | 17 | 204 | 29.1 |
| 2 | North Carolina | 7 | 97 | 75 | 23 | 195 | 27.9 |
| 3 | Virginia | 7 | 58 | 117 | 13 | 188 | 26.9 |
| 4 | Wake Forest | 6 | 49 | 82 | 20 | 151 | 25.2 |
| 5 | Duke | 7 | 69 | 94 | 11 | 174 | 24.9 |
| 6 | Miami (Florida) | 7 | 61 | 84 | 21 | 166 | 23.7 |
| 7 | North Carolina State | 7 | 54 | 92 | 19 | 165 | 23.6 |
| 8 | Clemson | 6 | 67 | 59 | 11 | 137 | 22.8 |
| 9 | Florida State | 7 | 70 | 62 | 20 | 152 | 21.7 |
| 10 | Syracuse | 7 | 76 | 53 | 12 | 141 | 20.1 |
| 11 | Virginia Tech | 7 | 68 | 61 | 10 | 139 | 19.9 |
| 12 | Louisville | 7 | 60 | 68 | 10 | 138 | 19.7 |
| 13 | Boston College | 6 | 67 | 36 | 13 | 116 | 19.3 |
| 13 | Georgia Tech | 6 | 56 | 49 | 11 | 116 | 19.3 |