2021 Atlantic Coast Conference Leaders First Downs - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Virginia | 11 | 74 | 200 | 23 | 297 | 27.0 |
| 2 | Wake Forest | 13 | 110 | 180 | 43 | 333 | 25.6 |
| 3 | Pittsburgh | 13 | 113 | 188 | 27 | 328 | 25.2 |
| 4 | Miami (Florida) | 11 | 83 | 141 | 39 | 263 | 23.9 |
| 5 | North Carolina | 12 | 134 | 119 | 28 | 281 | 23.4 |
| 6 | Duke | 11 | 103 | 117 | 18 | 238 | 21.6 |
| 7 | Louisville | 12 | 113 | 123 | 21 | 257 | 21.4 |
| 8 | North Carolina State | 11 | 72 | 140 | 20 | 232 | 21.1 |
| 9 | Florida State | 11 | 98 | 101 | 26 | 225 | 20.5 |
| 10 | Clemson | 12 | 100 | 106 | 25 | 231 | 19.3 |
| 11 | Syracuse | 11 | 122 | 71 | 17 | 210 | 19.1 |
| 12 | Virginia Tech | 12 | 117 | 89 | 19 | 225 | 18.8 |
| 13 | Boston College | 11 | 111 | 74 | 21 | 206 | 18.7 |
| 13 | Georgia Tech | 11 | 93 | 92 | 21 | 206 | 18.7 |