2021 Atlantic Coast Conference Leaders Total Offense - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Virginia | 5 | 490 | 2167 | 383 | 2657 | 6.94 | 531.4 |
| 2 | Louisville | 6 | 1325 | 1489 | 424 | 2814 | 6.64 | 469.0 |
| 3 | Wake Forest | 8 | 1138 | 2579 | 607 | 3717 | 6.12 | 464.6 |
| 4 | Pittsburgh | 7 | 1045 | 1971 | 526 | 3016 | 5.73 | 430.9 |
| 5 | Miami (Florida) | 5 | 491 | 1575 | 370 | 2066 | 5.58 | 413.2 |
| 6 | North Carolina | 6 | 949 | 1503 | 398 | 2452 | 6.16 | 408.7 |
| 7 | North Carolina State | 5 | 435 | 1586 | 344 | 2021 | 5.88 | 404.2 |
| 8 | Georgia Tech | 6 | 1031 | 1223 | 409 | 2254 | 5.51 | 375.7 |
| 9 | Duke | 5 | 949 | 929 | 356 | 1878 | 5.28 | 375.6 |
| 10 | Virginia Tech | 6 | 1174 | 979 | 403 | 2153 | 5.34 | 358.8 |
| 11 | Syracuse | 5 | 1144 | 598 | 315 | 1742 | 5.53 | 348.4 |
| 12 | Boston College | 6 | 866 | 1222 | 388 | 2088 | 5.38 | 348.0 |
| 13 | Florida State | 5 | 654 | 1001 | 292 | 1655 | 5.67 | 331.0 |
| 14 | Clemson | 7 | 903 | 1144 | 446 | 2047 | 4.59 | 292.4 |