2021 Atlantic Coast Conference Leaders Tackles For Loss - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Pittsburgh | 13 | 105.0 | 496 | 8.08 |
| 2 | Clemson | 12 | 82.0 | 362 | 6.83 |
| 3 | Miami (Florida) | 11 | 88.0 | 354 | 8.00 |
| 4 | Wake Forest | 13 | 88.0 | 338 | 6.77 |
| 5 | Louisville | 12 | 76.0 | 304 | 6.33 |
| 6 | Syracuse | 11 | 70.0 | 297 | 6.36 |
| 7 | North Carolina | 12 | 64.0 | 271 | 5.33 |
| 8 | North Carolina State | 11 | 74.0 | 260 | 6.73 |
| 9 | Florida State | 11 | 79.0 | 257 | 7.18 |
| 10 | Virginia Tech | 12 | 62.0 | 233 | 5.17 |
| 11 | Boston College | 11 | 49.0 | 231 | 4.46 |
| 12 | Duke | 11 | 56.0 | 210 | 5.09 |
| 13 | Georgia Tech | 11 | 51.0 | 206 | 4.64 |
| 14 | Virginia | 11 | 45.0 | 154 | 4.09 |