2021 American Athletic Conference Leaders Rushing Defense - In All Plays through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 12 | 390 | 1572 | 4.03 | 25 | 78 | 86 | 51 | 9 |
| 2 | East Carolina | 12 | 412 | 1940 | 4.71 | 20 | 90 | 100 | 60 | 23 |
| 3 | South Florida | 12 | 429 | 2487 | 5.80 | 28 | 97 | 118 | 77 | 23 |
| 4 | SMU | 12 | 438 | 1651 | 3.77 | 15 | 58 | 80 | 49 | 17 |
| 5 | Houston | 14 | 445 | 1515 | 3.40 | 13 | 79 | 80 | 47 | 14 |
| 6 | Tulsa | 13 | 479 | 1857 | 3.88 | 19 | 64 | 93 | 54 | 12 |
| 6 | UCF | 13 | 479 | 2070 | 4.32 | 24 | 79 | 111 | 72 | 18 |
| 8 | Tulane | 12 | 484 | 1901 | 3.93 | 25 | 68 | 107 | 60 | 18 |
| 9 | Memphis | 12 | 489 | 2005 | 4.10 | 22 | 57 | 125 | 61 | 13 |
| 10 | Temple | 12 | 555 | 2646 | 4.77 | 33 | 75 | 143 | 80 | 22 |
| 11 | Cincinnati | 14 | 583 | 2088 | 3.58 | 14 | 51 | 124 | 64 | 8 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||