2021 Mid-American Conference Leaders Rushing Defense - In The 2nd Half/Overtime through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Eastern Michigan | 13 | 260 | 1183 | 4.55 | 14 | 35 | 73 | 36 | 10 |
| 2 | Ball State | 13 | 264 | 1073 | 4.06 | 5 | 46 | 64 | 32 | 5 |
| 2 | Akron | 12 | 230 | 1463 | 6.36 | 17 | 46 | 73 | 51 | 14 |
| 4 | Toledo | 13 | 252 | 876 | 3.48 | 4 | 52 | 46 | 26 | 7 |
| 5 | Bowling Green | 12 | 279 | 1230 | 4.41 | 15 | 54 | 74 | 42 | 5 |
| 6 | Ohio | 12 | 248 | 1113 | 4.49 | 14 | 55 | 62 | 36 | 6 |
| 7 | Northern Illinois | 14 | 273 | 1549 | 5.67 | 15 | 60 | 79 | 53 | 16 |
| 8 | Central Michigan | 13 | 218 | 778 | 3.57 | 12 | 69 | 46 | 30 | 9 |
| 9 | Western Michigan | 13 | 220 | 806 | 3.66 | 12 | 74 | 52 | 30 | 11 |
| 10 | Buffalo | 12 | 239 | 1095 | 4.58 | 14 | 77 | 57 | 40 | 13 |
| 11 | Miami (Ohio) | 13 | 244 | 914 | 3.75 | 7 | 79 | 53 | 28 | 9 |
| 12 | Kent State | 14 | 293 | 1705 | 5.82 | 30 | 80 | 88 | 49 | 22 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||