2021 Conference USA Leaders Rushing Defense - On 3rd Down, 10+ Yards To Go through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Middle Tennessee | 8 | 15 | -22 | -1.47 | 0 | 12 | 2 | 2 | 0 |
| 2 | UAB | 10 | 13 | -4 | -0.31 | 0 | 10 | 1 | 1 | 0 |
| 3 | Southern Mississippi | 8 | 14 | 3 | 0.21 | 0 | 16 | 0 | 1 | 0 |
| 4 | UTSA | 11 | 25 | 6 | 0.24 | 0 | 13 | 3 | 4 | 0 |
| 5 | Old Dominion | 9 | 14 | 8 | 0.57 | 0 | 10 | 0 | 1 | 0 |
| 6 | Western Kentucky | 12 | 20 | 21 | 1.05 | 0 | 16 | 3 | 6 | 0 |
| 7 | UTEP | 10 | 18 | 31 | 1.72 | 0 | 10 | 0 | 1 | 0 |
| 8 | North Texas | 12 | 22 | 48 | 2.18 | 0 | 39 | 3 | 4 | 1 |
| 9 | Louisiana Tech | 9 | 17 | 73 | 4.29 | 0 | 23 | 3 | 5 | 1 |
| 10 | Rice | 8 | 15 | 87 | 5.80 | 0 | 42 | 2 | 3 | 2 |
| 11 | Florida International | 10 | 15 | 101 | 6.73 | 1 | 29 | 3 | 3 | 1 |
| 12 | Marshall | 12 | 25 | 112 | 4.48 | 0 | 43 | 5 | 7 | 3 |
| 13 | Florida Atlantic | 6 | 14 | 118 | 8.43 | 0 | 34 | 5 | 5 | 3 |
| 14 | Charlotte | 9 | 19 | 126 | 6.63 | 0 | 46 | 2 | 4 | 2 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||