2021 Big 12 Conference Leaders Total Defense - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 9 | 738 | 2168 | 606 | 2906 | 4.80 | 322.9 |
| 2 | Iowa State | 7 | 972 | 1295 | 417 | 2267 | 5.44 | 323.9 |
| 3 | Baylor | 8 | 1017 | 1839 | 542 | 2856 | 5.27 | 357.0 |
| 4 | West Virginia | 8 | 1224 | 1822 | 519 | 3046 | 5.87 | 380.8 |
| 5 | Kansas State | 6 | 847 | 1480 | 400 | 2327 | 5.82 | 387.8 |
| 6 | Texas Tech | 7 | 731 | 2088 | 498 | 2819 | 5.66 | 402.7 |
| 7 | Oklahoma | 6 | 883 | 1536 | 428 | 2419 | 5.65 | 403.2 |
| 8 | Texas | 8 | 1730 | 1875 | 561 | 3605 | 6.43 | 450.6 |
| 9 | Kansas | 7 | 1803 | 1660 | 447 | 3463 | 7.75 | 494.7 |
| 10 | TCU | 7 | 1845 | 1837 | 467 | 3682 | 7.88 | 526.0 |