2021 Big 12 Conference Leaders Total Defense - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 4 | 387 | 541 | 221 | 928 | 4.20 | 232.0 |
| 2 | Iowa State | 5 | 573 | 910 | 321 | 1483 | 4.62 | 296.6 |
| 3 | Kansas State | 6 | 739 | 1142 | 367 | 1881 | 5.13 | 313.5 |
| 4 | Baylor | 5 | 474 | 1233 | 337 | 1707 | 5.07 | 341.4 |
| 5 | West Virginia | 4 | 545 | 868 | 250 | 1413 | 5.65 | 353.3 |
| 6 | Texas | 4 | 689 | 813 | 286 | 1502 | 5.25 | 375.5 |
| 7 | Oklahoma | 6 | 739 | 1744 | 396 | 2483 | 6.27 | 413.8 |
| 8 | Texas Tech | 5 | 1024 | 1056 | 313 | 2080 | 6.65 | 416.0 |
| 9 | TCU | 4 | 758 | 964 | 260 | 1722 | 6.62 | 430.5 |
| 10 | Kansas | 4 | 1030 | 1079 | 299 | 2109 | 7.05 | 527.3 |