2021 Atlantic Coast Conference Leaders Rushing Defense - In The 2nd Half/Overtime through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Florida State | 12 | 237 | 785 | 3.31 | 8 | 32 | 44 | 31 | 3 |
| 2 | Clemson | 13 | 231 | 649 | 2.81 | 3 | 51 | 40 | 21 | 4 |
| 3 | Pittsburgh | 14 | 225 | 678 | 3.01 | 6 | 38 | 41 | 24 | 6 |
| 4 | Boston College | 12 | 231 | 985 | 4.26 | 8 | 51 | 50 | 29 | 7 |
| 5 | Miami (Florida) | 12 | 201 | 666 | 3.31 | 6 | 44 | 39 | 23 | 8 |
| 5 | Syracuse | 12 | 226 | 859 | 3.80 | 7 | 65 | 52 | 24 | 8 |
| 5 | Georgia Tech | 12 | 256 | 1193 | 4.66 | 8 | 68 | 59 | 32 | 8 |
| 8 | Virginia Tech | 13 | 273 | 1244 | 4.56 | 8 | 61 | 72 | 43 | 9 |
| 9 | North Carolina State | 12 | 207 | 817 | 3.95 | 5 | 48 | 40 | 29 | 11 |
| 10 | North Carolina | 13 | 244 | 1254 | 5.14 | 13 | 91 | 71 | 37 | 12 |
| 10 | Duke | 12 | 244 | 1272 | 5.21 | 11 | 62 | 62 | 33 | 12 |
| 12 | Louisville | 13 | 261 | 1315 | 5.04 | 12 | 75 | 74 | 54 | 13 |
| 13 | Wake Forest | 14 | 258 | 1289 | 5.00 | 12 | 71 | 66 | 48 | 14 |
| 14 | Virginia | 12 | 254 | 1559 | 6.14 | 13 | 71 | 67 | 43 | 18 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||