2021 Atlantic Coast Conference Leaders Scoring Defense - Games at Home Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 6 | 8 | 7 | 5 | 1 | 1 | 78 | 13.0 |
| 2 | North Carolina State | 7 | 13 | 8 | 13 | 0 | 0 | 115 | 16.4 |
| 3 | Wake Forest | 6 | 15 | 6 | 13 | 1 | 0 | 123 | 20.5 |
| 4 | Virginia | 7 | 18 | 7 | 15 | 1 | 1 | 148 | 21.1 |
| 5 | Virginia Tech | 7 | 20 | 4 | 18 | 1 | 0 | 152 | 21.7 |
| 6 | Syracuse | 7 | 19 | 8 | 16 | 1 | 0 | 156 | 22.3 |
| 7 | Boston College | 6 | 16 | 7 | 16 | 0 | 2 | 137 | 22.8 |
| 8 | Louisville | 7 | 21 | 8 | 21 | 0 | 0 | 171 | 24.4 |
| 9 | Pittsburgh | 7 | 23 | 5 | 21 | 0 | 0 | 174 | 24.9 |
| 10 | Miami (Florida) | 7 | 21 | 9 | 18 | 2 | 1 | 177 | 25.3 |
| 11 | Florida State | 7 | 24 | 5 | 22 | 0 | 0 | 181 | 25.9 |
| 12 | North Carolina | 7 | 27 | 6 | 25 | 2 | 0 | 209 | 29.9 |
| 13 | Georgia Tech | 6 | 25 | 9 | 24 | 1 | 0 | 203 | 33.8 |
| 14 | Duke | 7 | 33 | 13 | 30 | 0 | 0 | 267 | 38.1 |