2021 Atlantic Coast Conference Leaders Scoring Defense - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 6 | 12 | 7 | 9 | 1 | 0 | 104 | 17.3 |
| 2 | Syracuse | 5 | 19 | 6 | 16 | 1 | 0 | 150 | 30.0 |
| 3 | North Carolina State | 4 | 16 | 3 | 16 | 0 | 0 | 121 | 30.3 |
| 4 | Pittsburgh | 6 | 24 | 6 | 21 | 1 | 0 | 185 | 30.8 |
| 5 | Boston College | 3 | 10 | 7 | 10 | 0 | 1 | 93 | 31.0 |
| 6 | Florida State | 5 | 21 | 5 | 19 | 1 | 0 | 162 | 32.4 |
| 7 | Virginia Tech | 5 | 22 | 4 | 20 | 1 | 0 | 166 | 33.2 |
| 8 | Miami (Florida) | 5 | 20 | 10 | 19 | 0 | 0 | 169 | 33.8 |
| 9 | Louisville | 7 | 32 | 11 | 31 | 0 | 0 | 256 | 36.6 |
| 10 | Georgia Tech | 6 | 29 | 6 | 27 | 1 | 0 | 221 | 36.8 |
| 11 | North Carolina | 7 | 32 | 12 | 28 | 2 | 0 | 260 | 37.1 |
| 12 | Virginia | 5 | 27 | 6 | 27 | 0 | 0 | 207 | 41.4 |
| 13 | Wake Forest | 4 | 25 | 5 | 24 | 1 | 0 | 191 | 47.8 |
| 14 | Duke | 3 | 17 | 9 | 17 | 0 | 0 | 146 | 48.7 |