2021 Atlantic Coast Conference Leaders Scoring Defense - Games in December/January Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 1 | 1 | 2 | 1 | 0 | 0 | 13 | 13.0 |
| 2 | Pittsburgh | 2 | 7 | 1 | 5 | 1 | 0 | 52 | 26.0 |
| 3 | Wake Forest | 2 | 7 | 2 | 7 | 0 | 0 | 55 | 27.5 |
| 4 | Louisville | 1 | 4 | 1 | 4 | 0 | 0 | 31 | 31.0 |
| 5 | North Carolina | 1 | 4 | 3 | 3 | 1 | 0 | 38 | 38.0 |
| 6 | Virginia Tech | 1 | 7 | 2 | 6 | 0 | 0 | 54 | 54.0 |