2021 Atlantic Coast Conference Leaders Opponent First Downs - Games Won Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Georgia Tech | 3 | 22 | 31 | 5 | 58 | 19.3 |
| 2 | Miami (Florida) | 7 | 45 | 74 | 7 | 126 | 18.0 |
| 3 | Duke | 3 | 27 | 27 | 8 | 62 | 20.7 |
| 4 | Syracuse | 5 | 44 | 34 | 9 | 87 | 17.4 |
| 5 | Clemson | 10 | 49 | 92 | 11 | 152 | 15.2 |
| 5 | Virginia Tech | 6 | 48 | 56 | 11 | 115 | 19.2 |
| 7 | Virginia | 6 | 42 | 61 | 12 | 115 | 19.2 |
| 8 | Boston College | 6 | 44 | 47 | 13 | 104 | 17.3 |
| 8 | Florida State | 5 | 46 | 41 | 13 | 100 | 20.0 |
| 10 | Louisville | 6 | 53 | 51 | 14 | 118 | 19.7 |
| 11 | North Carolina | 6 | 52 | 70 | 19 | 141 | 23.5 |
| 12 | Wake Forest | 11 | 109 | 106 | 20 | 235 | 21.4 |
| 13 | North Carolina State | 9 | 61 | 66 | 23 | 150 | 16.7 |
| 14 | Pittsburgh | 11 | 62 | 111 | 26 | 199 | 18.1 |