2021 Atlantic Coast Conference Leaders Tackles For Loss - Games vs. Conference Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Pittsburgh | 9 | 76.0 | 343 | 8.44 |
| 2 | Wake Forest | 10 | 69.0 | 281 | 6.90 |
| 3 | Miami (Florida) | 8 | 64.0 | 264 | 8.00 |
| 4 | Clemson | 8 | 60.0 | 268 | 7.50 |
| 5 | North Carolina State | 8 | 59.0 | 206 | 7.38 |
| 6 | Louisville | 8 | 56.0 | 228 | 7.00 |
| 7 | Florida State | 8 | 54.0 | 189 | 6.75 |
| 8 | North Carolina | 9 | 46.0 | 217 | 5.11 |
| 9 | Syracuse | 8 | 45.0 | 205 | 5.63 |
| 9 | Virginia Tech | 8 | 45.0 | 174 | 5.63 |
| 11 | Georgia Tech | 8 | 43.0 | 161 | 5.38 |
| 12 | Boston College | 8 | 37.0 | 188 | 4.63 |
| 12 | Duke | 8 | 37.0 | 133 | 4.63 |
| 14 | Virginia | 8 | 34.0 | 125 | 4.25 |