2021 Atlantic Coast Conference Leaders Sacks - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Pittsburgh | 7 | 31.0 | 221 | 4.43 |
| 2 | Clemson | 6 | 25.0 | 179 | 4.17 |
| 3 | Wake Forest | 9 | 29.0 | 152 | 3.22 |
| 4 | Miami (Florida) | 6 | 20.0 | 142 | 3.33 |
| 5 | Louisville | 5 | 19.0 | 131 | 3.80 |
| 6 | North Carolina State | 7 | 22.0 | 128 | 3.14 |
| 7 | Boston College | 8 | 14.0 | 125 | 1.75 |
| 8 | Virginia Tech | 7 | 17.0 | 115 | 2.43 |
| 9 | Duke | 8 | 15.0 | 108 | 1.88 |
| 10 | Syracuse | 6 | 15.0 | 105 | 2.50 |
| 11 | Georgia Tech | 5 | 12.0 | 81 | 2.40 |
| 12 | North Carolina | 5 | 10.0 | 67 | 2.00 |
| 13 | Virginia | 6 | 10.0 | 53 | 1.67 |
| 14 | Florida State | 6 | 12.0 | 51 | 2.00 |