2021 Atlantic Coast Conference Leaders Interceptions - Games Lost Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Florida State | 7 | 7 | 78 | 0 | 1.00 |
| 2 | Virginia | 6 | 4 | 99 | 0 | 0.67 |
| 2 | Virginia Tech | 7 | 4 | 58 | 1 | 0.57 |
| 4 | North Carolina State | 3 | 3 | 5 | 0 | 1.00 |
| 4 | Boston College | 6 | 3 | 12 | 0 | 0.50 |
| 4 | Louisville | 7 | 3 | 64 | 0 | 0.43 |
| 4 | Syracuse | 7 | 3 | 9 | 0 | 0.43 |
| 4 | Duke | 9 | 3 | 46 | 0 | 0.33 |
| 9 | Pittsburgh | 3 | 2 | 0 | 0 | 0.67 |
| 9 | Miami (Florida) | 5 | 2 | 42 | 1 | 0.40 |
| 9 | North Carolina | 7 | 2 | 0 | 0 | 0.29 |
| 12 | Clemson | 3 | 1 | 3 | 0 | 0.33 |
| 12 | Wake Forest | 3 | 1 | 0 | 0 | 0.33 |