2021 Atlantic Coast Conference Leaders Interceptions - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | North Carolina State | 2 | 5 | 22 | 0 | 2.50 |
| 2 | Wake Forest | 2 | 3 | 130 | 1 | 1.50 |
| 2 | Florida State | 2 | 3 | 75 | 1 | 1.50 |
| 2 | Virginia Tech | 2 | 3 | 70 | 1 | 1.50 |
| 5 | Clemson | 1 | 2 | 2 | 0 | 2.00 |
| 5 | Boston College | 2 | 2 | -3 | 0 | 1.00 |
| 7 | Miami (Florida) | 1 | 1 | 0 | 0 | 1.00 |
| 7 | Louisville | 2 | 1 | 66 | 1 | 0.50 |
| 7 | Syracuse | 2 | 1 | 23 | 0 | 0.50 |
| 7 | North Carolina | 2 | 1 | 17 | 0 | 0.50 |
| 7 | Virginia | 2 | 1 | 0 | 0 | 0.50 |