2021 American Athletic Conference Leaders Interceptions - Games Lost Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | South Florida | 10 | 8 | 249 | 1 | 0.80 |
| 2 | Tulane | 10 | 7 | 62 | 0 | 0.70 |
| 3 | East Carolina | 5 | 5 | 24 | 0 | 1.00 |
| 3 | Memphis | 6 | 5 | 26 | 0 | 0.83 |
| 3 | Navy | 8 | 5 | 23 | 0 | 0.63 |
| 6 | Tulsa | 6 | 4 | 55 | 1 | 0.67 |
| 6 | Temple | 9 | 4 | 45 | 0 | 0.44 |
| 8 | SMU | 4 | 3 | 19 | 0 | 0.75 |
| 9 | UCF | 4 | 2 | 23 | 0 | 0.50 |
| 10 | Cincinnati | 1 | 1 | 0 | 0 | 1.00 |