2021 Big Ten Conference Leaders Passes Defended - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Ohio State | 4 | 4 | 22 | 26 | 6.50 |
| 2 | Iowa | 4 | 4 | 19 | 23 | 5.75 |
| 3 | Michigan State | 4 | 4 | 18 | 22 | 5.50 |
| 3 | Minnesota | 4 | 3 | 19 | 22 | 5.50 |
| 3 | Rutgers | 4 | 3 | 19 | 22 | 5.50 |
| 6 | Michigan | 4 | 1 | 19 | 20 | 5.00 |
| 7 | Penn State | 4 | 5 | 13 | 18 | 4.50 |
| 7 | Purdue | 4 | 2 | 16 | 18 | 4.50 |
| 9 | Maryland | 4 | 3 | 14 | 17 | 4.25 |
| 10 | Nebraska | 3 | 4 | 12 | 16 | 5.33 |
| 11 | Illinois | 3 | 2 | 13 | 15 | 5.00 |
| 12 | Northwestern | 3 | 3 | 11 | 14 | 4.67 |
| 12 | Indiana | 3 | 1 | 13 | 14 | 4.67 |
| 14 | Wisconsin | 4 | 2 | 8 | 10 | 2.50 |