2022 Big 12 Conference Leaders Passes Defended - Games vs. FBS Teams With Non-Winning Record Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma | 7 | 10 | 22 | 32 | 4.57 |
| 2 | TCU | 6 | 5 | 25 | 30 | 5.00 |
| 2 | Oklahoma State | 7 | 8 | 22 | 30 | 4.29 |
| 4 | Texas | 6 | 6 | 21 | 27 | 4.50 |
| 5 | Baylor | 5 | 6 | 20 | 26 | 5.20 |
| 5 | Kansas State | 6 | 8 | 18 | 26 | 4.33 |
| 7 | Kansas | 4 | 5 | 12 | 17 | 4.25 |
| 8 | Texas Tech | 5 | 5 | 11 | 16 | 3.20 |
| 8 | West Virginia | 5 | 2 | 14 | 16 | 3.20 |
| 10 | Iowa State | 4 | 1 | 12 | 13 | 3.25 |