2022 Big 12 Conference Leaders Passes Defended - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma | 2 | 2 | 9 | 11 | 5.50 |
| 2 | Oklahoma State | 1 | 1 | 6 | 7 | 7.00 |
| 2 | Texas | 2 | 2 | 5 | 7 | 3.50 |
| 2 | Baylor | 3 | 0 | 7 | 7 | 2.33 |
| 5 | Kansas State | 1 | 2 | 4 | 6 | 6.00 |
| 5 | TCU | 1 | 2 | 4 | 6 | 6.00 |
| 7 | Iowa State | 1 | 2 | 3 | 5 | 5.00 |
| 7 | Texas Tech | 1 | 1 | 4 | 5 | 5.00 |
| 9 | Kansas | 1 | 1 | 2 | 3 | 3.00 |