2022 Big 12 Conference Leaders Passes Defended - Games in November Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | TCU | 4 | 5 | 23 | 28 | 7.00 |
| 2 | Oklahoma | 4 | 7 | 19 | 26 | 6.50 |
| 3 | Oklahoma State | 4 | 5 | 12 | 17 | 4.25 |
| 3 | Kansas | 4 | 3 | 14 | 17 | 4.25 |
| 5 | Texas | 4 | 3 | 13 | 16 | 4.00 |
| 6 | Baylor | 4 | 4 | 10 | 14 | 3.50 |
| 6 | Iowa State | 4 | 3 | 11 | 14 | 3.50 |
| 6 | West Virginia | 4 | 1 | 13 | 14 | 3.50 |
| 9 | Kansas State | 4 | 4 | 8 | 12 | 3.00 |
| 9 | Texas Tech | 4 | 2 | 10 | 12 | 3.00 |