2021 American Athletic Conference Leaders Passing Defense - In The 2nd Half/Overtime through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Temple | 12 | 128 | 81 | 63.3 | 969 | 12 | 1 | 156.25 | 46 | 46 | 22 | 11 |
| 2 | Navy | 12 | 143 | 96 | 67.1 | 1168 | 6 | 4 | 144.00 | 51 | 50 | 26 | 10 |
| 3 | South Florida | 12 | 166 | 102 | 61.4 | 1195 | 9 | 4 | 134.99 | 47 | 62 | 26 | 10 |
| 4 | UCF | 13 | 211 | 111 | 52.6 | 1250 | 6 | 5 | 107.02 | 49 | 59 | 27 | 13 |
| 5 | Houston | 14 | 210 | 111 | 52.9 | 1254 | 9 | 9 | 108.59 | 50 | 48 | 28 | 14 |
| 6 | East Carolina | 12 | 182 | 100 | 54.9 | 1279 | 4 | 12 | 108.04 | 68 | 53 | 29 | 10 |
| 7 | Tulane | 12 | 160 | 101 | 63.1 | 1296 | 10 | 5 | 145.55 | 59 | 54 | 30 | 15 |
| 8 | Cincinnati | 14 | 198 | 104 | 52.5 | 1311 | 7 | 9 | 110.73 | 80 | 61 | 32 | 13 |
| 9 | Tulsa | 13 | 207 | 118 | 57.0 | 1504 | 11 | 3 | 132.68 | 53 | 61 | 38 | 16 |
| 10 | Memphis | 12 | 213 | 133 | 62.4 | 1512 | 12 | 7 | 134.09 | 89 | 73 | 33 | 10 |
| 11 | SMU | 12 | 203 | 116 | 57.1 | 1610 | 14 | 7 | 139.62 | 48 | 70 | 37 | 20 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||