2021 American Athletic Conference Leaders Passing Defense - In The 4th Quarter through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Temple | 11 | 56 | 35 | 62.5 | 368 | 5 | 1 | 143.60 | 35 | 19 | 9 | 2 |
| 2 | Tulane | 12 | 62 | 40 | 64.5 | 453 | 6 | 3 | 148.14 | 44 | 23 | 9 | 5 |
| 3 | South Florida | 12 | 72 | 42 | 58.3 | 456 | 4 | 1 | 127.08 | 46 | 22 | 9 | 3 |
| 4 | Houston | 13 | 113 | 51 | 45.1 | 551 | 3 | 6 | 84.23 | 50 | 22 | 13 | 5 |
| 5 | SMU | 12 | 87 | 44 | 50.6 | 575 | 5 | 4 | 115.87 | 42 | 30 | 11 | 6 |
| 6 | East Carolina | 12 | 101 | 56 | 55.4 | 649 | 1 | 7 | 98.84 | 59 | 28 | 13 | 5 |
| 6 | Navy | 11 | 67 | 44 | 65.7 | 649 | 5 | 1 | 168.68 | 47 | 24 | 15 | 8 |
| 8 | UCF | 12 | 117 | 61 | 52.1 | 684 | 3 | 5 | 101.16 | 45 | 34 | 14 | 6 |
| 9 | Cincinnati | 14 | 118 | 62 | 52.5 | 755 | 6 | 5 | 114.59 | 53 | 36 | 18 | 8 |
| 10 | Tulsa | 12 | 101 | 56 | 55.4 | 776 | 7 | 2 | 138.90 | 49 | 30 | 21 | 9 |
| 11 | Memphis | 12 | 111 | 70 | 63.1 | 833 | 10 | 5 | 146.82 | 89 | 37 | 15 | 6 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||