2021 American Athletic Conference Leaders Passing Defense - When Winning By 15+ Pts through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 1 | 9 | 6 | 66.7 | 49 | 0 | 0 | 112.40 | 16 | 3 | 1 | 0 |
| 2 | Temple | 2 | 16 | 7 | 43.8 | 67 | 1 | 0 | 99.56 | 16 | 5 | 1 | 0 |
| 3 | South Florida | 2 | 35 | 19 | 54.3 | 178 | 1 | 1 | 100.73 | 19 | 11 | 3 | 0 |
| 4 | Tulane | 2 | 54 | 33 | 61.1 | 320 | 3 | 2 | 121.81 | 52 | 12 | 6 | 2 |
| 5 | Tulsa | 4 | 49 | 31 | 63.3 | 328 | 3 | 0 | 139.70 | 35 | 14 | 8 | 3 |
| 6 | East Carolina | 4 | 72 | 37 | 51.4 | 430 | 1 | 4 | 95.02 | 59 | 17 | 10 | 3 |
| 7 | UCF | 4 | 104 | 55 | 52.9 | 528 | 2 | 5 | 92.27 | 47 | 28 | 7 | 5 |
| 8 | Memphis | 6 | 65 | 45 | 69.2 | 537 | 6 | 1 | 166.01 | 89 | 23 | 13 | 3 |
| 9 | Houston | 7 | 102 | 55 | 53.9 | 584 | 4 | 10 | 95.34 | 43 | 24 | 10 | 6 |
| 10 | SMU | 7 | 111 | 54 | 48.6 | 836 | 5 | 4 | 119.58 | 59 | 36 | 16 | 10 |
| 11 | Cincinnati | 12 | 156 | 84 | 53.8 | 1005 | 6 | 4 | 115.52 | 80 | 48 | 25 | 10 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||