2021 American Athletic Conference Leaders Passing Defense - On 3rd Down, 10+ Yards To Go through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | South Florida | 9 | 23 | 8 | 34.8 | 50 | 1 | 4 | 32.61 | 19 | 2 | 1 | 0 |
| 2 | Temple | 11 | 25 | 9 | 36.0 | 114 | 0 | 0 | 74.30 | 25 | 4 | 3 | 1 |
| 3 | Navy | 12 | 21 | 13 | 61.9 | 117 | 0 | 0 | 108.71 | 15 | 1 | 2 | 0 |
| 4 | East Carolina | 11 | 28 | 19 | 67.9 | 176 | 0 | 1 | 113.52 | 24 | 7 | 2 | 0 |
| 5 | Memphis | 10 | 27 | 15 | 55.6 | 185 | 0 | 1 | 105.71 | 21 | 7 | 8 | 0 |
| 6 | Houston | 11 | 37 | 21 | 56.8 | 213 | 2 | 3 | 106.74 | 34 | 5 | 2 | 2 |
| 7 | Tulsa | 11 | 36 | 21 | 58.3 | 280 | 2 | 1 | 136.44 | 35 | 7 | 6 | 4 |
| 8 | UCF | 12 | 39 | 25 | 64.1 | 351 | 3 | 1 | 159.95 | 33 | 13 | 10 | 4 |
| 9 | SMU | 11 | 31 | 19 | 61.3 | 363 | 2 | 0 | 180.94 | 55 | 9 | 9 | 6 |
| 10 | Cincinnati | 14 | 48 | 23 | 47.9 | 375 | 1 | 4 | 103.75 | 53 | 15 | 11 | 3 |
| 10 | Tulane | 11 | 32 | 21 | 65.6 | 375 | 2 | 2 | 172.20 | 52 | 13 | 8 | 4 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||