2021 American Athletic Conference Leaders Scoring Defense - All Games through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 14 | 28 | 13 | 25 | 1 | 1 | 236 | 16.9 |
| 2 | Houston | 14 | 36 | 11 | 33 | 2 | 0 | 286 | 20.4 |
| 3 | UCF | 13 | 40 | 13 | 40 | 0 | 0 | 319 | 24.5 |
| 4 | East Carolina | 12 | 41 | 10 | 35 | 2 | 0 | 315 | 26.3 |
| 5 | Tulsa | 13 | 42 | 17 | 39 | 2 | 0 | 346 | 26.6 |
| 6 | Navy | 12 | 43 | 11 | 40 | 2 | 2 | 339 | 28.3 |
| 7 | SMU | 12 | 44 | 13 | 38 | 0 | 0 | 341 | 28.4 |
| 8 | Memphis | 12 | 44 | 15 | 40 | 1 | 0 | 351 | 29.3 |
| 9 | Tulane | 12 | 53 | 14 | 48 | 0 | 0 | 408 | 34.0 |
| 10 | South Florida | 12 | 55 | 11 | 51 | 0 | 1 | 416 | 34.7 |
| 11 | Temple | 12 | 59 | 12 | 56 | 1 | 1 | 450 | 37.5 |