2021 American Athletic Conference Leaders Scoring Defense - Games in November Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 4 | 9 | 4 | 7 | 1 | 0 | 75 | 18.8 |
| 2 | Houston | 4 | 10 | 3 | 9 | 1 | 0 | 80 | 20.0 |
| 3 | Tulane | 4 | 10 | 4 | 9 | 0 | 0 | 81 | 20.3 |
| 4 | Tulsa | 4 | 10 | 4 | 10 | 0 | 0 | 82 | 20.5 |
| 5 | UCF | 4 | 11 | 6 | 11 | 0 | 0 | 95 | 23.8 |
| 6 | East Carolina | 4 | 14 | 2 | 12 | 0 | 0 | 102 | 25.5 |
| 7 | Memphis | 4 | 14 | 5 | 13 | 1 | 0 | 114 | 28.5 |
| 8 | Navy | 3 | 10 | 4 | 8 | 2 | 1 | 86 | 28.7 |
| 9 | SMU | 4 | 19 | 2 | 18 | 0 | 0 | 138 | 34.5 |
| 10 | South Florida | 4 | 21 | 4 | 21 | 0 | 1 | 161 | 40.3 |
| 11 | Temple | 4 | 21 | 6 | 20 | 0 | 0 | 164 | 41.0 |