2021 Mid-American Conference Leaders Total Defense - Games Won Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Akron | 2 | 136 | 374 | 125 | 510 | 4.08 | 255.0 |
| 2 | Western Michigan | 8 | 891 | 1343 | 441 | 2234 | 5.07 | 279.3 |
| 3 | Bowling Green | 4 | 593 | 571 | 269 | 1164 | 4.33 | 291.0 |
| 4 | Buffalo | 4 | 724 | 450 | 253 | 1174 | 4.64 | 293.5 |
| 5 | Toledo | 7 | 969 | 1162 | 468 | 2131 | 4.55 | 304.4 |
| 6 | Miami (Ohio) | 7 | 613 | 1652 | 462 | 2265 | 4.90 | 323.6 |
| 7 | Central Michigan | 9 | 897 | 2064 | 605 | 2961 | 4.89 | 329.0 |
| 8 | Ball State | 6 | 723 | 1549 | 444 | 2272 | 5.12 | 378.7 |
| 9 | Northern Illinois | 9 | 1582 | 1920 | 586 | 3502 | 5.98 | 389.1 |
| 10 | Eastern Michigan | 7 | 1071 | 1932 | 476 | 3003 | 6.31 | 429.0 |
| 11 | Kent State | 7 | 992 | 2016 | 554 | 3008 | 5.43 | 429.7 |
| 12 | Ohio | 3 | 287 | 1067 | 228 | 1354 | 5.94 | 451.3 |