2022 Atlantic Coast Conference Leaders Passes Defended - Games vs. FBS Teams With Winning Record Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | North Carolina State | 9 | 15 | 31 | 46 | 5.11 |
| 2 | Louisville | 10 | 10 | 34 | 44 | 4.40 |
| 3 | Clemson | 9 | 7 | 35 | 42 | 4.67 |
| 4 | Wake Forest | 8 | 5 | 34 | 39 | 4.88 |
| 5 | Boston College | 8 | 4 | 28 | 32 | 4.00 |
| 6 | North Carolina | 7 | 3 | 28 | 31 | 4.43 |
| 6 | Georgia Tech | 8 | 5 | 26 | 31 | 3.88 |
| 8 | Pittsburgh | 6 | 5 | 25 | 30 | 5.00 |
| 9 | Miami (Florida) | 7 | 7 | 21 | 28 | 4.00 |
| 10 | Syracuse | 9 | 8 | 19 | 27 | 3.00 |
| 11 | Duke | 4 | 4 | 18 | 22 | 5.50 |
| 12 | Virginia Tech | 5 | 2 | 19 | 21 | 4.20 |
| 13 | Virginia | 6 | 4 | 15 | 19 | 3.17 |
| 13 | Florida State | 6 | 3 | 16 | 19 | 3.17 |