2022 Atlantic Coast Conference Leaders Passes Defended - Games vs. FBS Teams With Non-Winning Record Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Duke | 8 | 6 | 38 | 44 | 5.50 |
| 2 | Pittsburgh | 6 | 9 | 34 | 43 | 7.17 |
| 3 | Clemson | 4 | 5 | 28 | 33 | 8.25 |
| 4 | Florida State | 6 | 5 | 24 | 29 | 4.83 |
| 5 | Wake Forest | 4 | 2 | 23 | 25 | 6.25 |
| 6 | North Carolina | 6 | 5 | 18 | 23 | 3.83 |
| 7 | Virginia Tech | 5 | 2 | 20 | 22 | 4.40 |
| 8 | Miami (Florida) | 4 | 4 | 17 | 21 | 5.25 |
| 9 | Virginia | 3 | 1 | 19 | 20 | 6.67 |
| 10 | North Carolina State | 3 | 2 | 11 | 13 | 4.33 |
| 11 | Georgia Tech | 3 | 3 | 8 | 11 | 3.67 |
| 12 | Louisville | 3 | 5 | 4 | 9 | 3.00 |
| 12 | Syracuse | 3 | 1 | 8 | 9 | 3.00 |
| 14 | Boston College | 3 | 1 | 7 | 8 | 2.67 |