2022 Atlantic Coast Conference Leaders Passes Defended - Games Lost Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Virginia Tech | 8 | 3 | 33 | 36 | 4.50 |
| 2 | Boston College | 9 | 3 | 30 | 33 | 3.67 |
| 3 | Miami (Florida) | 7 | 6 | 22 | 28 | 4.00 |
| 4 | Virginia | 7 | 4 | 22 | 26 | 3.71 |
| 5 | Wake Forest | 5 | 1 | 23 | 24 | 4.80 |
| 6 | North Carolina State | 5 | 6 | 17 | 23 | 4.60 |
| 7 | Georgia Tech | 7 | 4 | 17 | 21 | 3.00 |
| 8 | Pittsburgh | 4 | 1 | 16 | 17 | 4.25 |
| 8 | North Carolina | 5 | 2 | 15 | 17 | 3.40 |
| 10 | Syracuse | 6 | 5 | 11 | 16 | 2.67 |
| 11 | Duke | 4 | 2 | 11 | 13 | 3.25 |
| 12 | Clemson | 3 | 2 | 8 | 10 | 3.33 |
| 12 | Florida State | 3 | 1 | 9 | 10 | 3.33 |
| 12 | Louisville | 5 | 3 | 7 | 10 | 2.00 |