2022 Atlantic Coast Conference Leaders Passes Defended - Games at Home Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 7 | 2 | 51 | 53 | 7.57 |
| 2 | Clemson | 7 | 10 | 34 | 44 | 6.29 |
| 3 | Wake Forest | 7 | 5 | 38 | 43 | 6.14 |
| 4 | North Carolina State | 7 | 12 | 30 | 42 | 6.00 |
| 5 | Louisville | 6 | 11 | 22 | 33 | 5.50 |
| 5 | Florida State | 7 | 3 | 30 | 33 | 4.71 |
| 7 | Duke | 6 | 3 | 26 | 29 | 4.83 |
| 8 | North Carolina | 6 | 3 | 25 | 28 | 4.67 |
| 8 | Miami (Florida) | 7 | 9 | 19 | 28 | 4.00 |
| 10 | Virginia | 6 | 2 | 24 | 26 | 4.33 |
| 11 | Boston College | 6 | 5 | 20 | 25 | 4.17 |
| 11 | Syracuse | 7 | 6 | 19 | 25 | 3.57 |
| 13 | Georgia Tech | 6 | 7 | 13 | 20 | 3.33 |
| 14 | Virginia Tech | 5 | 2 | 16 | 18 | 3.60 |