2022 Atlantic Coast Conference Leaders Passes Defended - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Georgia Tech | 4 | 1 | 15 | 16 | 4.00 |
| 2 | North Carolina | 4 | 1 | 14 | 15 | 3.75 |
| 3 | Clemson | 4 | 2 | 12 | 14 | 3.50 |
| 4 | Boston College | 3 | 1 | 12 | 13 | 4.33 |
| 5 | Louisville | 3 | 4 | 8 | 12 | 4.00 |
| 5 | Syracuse | 4 | 5 | 7 | 12 | 3.00 |
| 7 | Miami (Florida) | 3 | 3 | 8 | 11 | 3.67 |
| 8 | Pittsburgh | 2 | 4 | 6 | 10 | 5.00 |
| 8 | Wake Forest | 2 | 0 | 10 | 10 | 5.00 |
| 10 | Duke | 1 | 2 | 6 | 8 | 8.00 |
| 10 | North Carolina State | 2 | 2 | 6 | 8 | 4.00 |
| 12 | Virginia Tech | 1 | 1 | 4 | 5 | 5.00 |
| 12 | Florida State | 2 | 0 | 5 | 5 | 2.50 |
| 14 | Virginia | 1 | 0 | 4 | 4 | 4.00 |