2021 Big 12 Conference Leaders First Downs - Games in November Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 4 | 45 | 42 | 13 | 100 | 25.0 |
| 2 | Iowa State | 4 | 25 | 62 | 9 | 96 | 24.0 |
| 3 | Baylor | 4 | 44 | 37 | 7 | 88 | 22.0 |
| 4 | West Virginia | 4 | 33 | 43 | 6 | 82 | 20.5 |
| 5 | TCU | 4 | 37 | 36 | 4 | 77 | 19.3 |
| 5 | Texas | 4 | 36 | 38 | 3 | 77 | 19.3 |
| 7 | Kansas | 4 | 29 | 39 | 5 | 73 | 18.3 |
| 8 | Oklahoma | 3 | 21 | 26 | 6 | 53 | 17.7 |
| 9 | Texas Tech | 3 | 17 | 26 | 6 | 49 | 16.3 |
| 10 | Kansas State | 4 | 31 | 26 | 5 | 62 | 15.5 |