2021 American Athletic Conference Leaders Interceptions - Games Won Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Cincinnati | 13 | 18 | 214 | 1 | 1.38 |
| 2 | Houston | 12 | 14 | 210 | 2 | 1.17 |
| 3 | East Carolina | 7 | 10 | 123 | 2 | 1.43 |
| 4 | SMU | 8 | 7 | 101 | 0 | 0.88 |
| 5 | Tulane | 2 | 3 | 94 | 1 | 1.50 |
| 6 | UCF | 9 | 9 | 91 | 0 | 1.00 |
| 7 | Tulsa | 7 | 7 | 60 | 0 | 1.00 |
| 8 | Memphis | 6 | 4 | 15 | 0 | 0.67 |
| 9 | Temple | 3 | 2 | 11 | 1 | 0.67 |
| 10 | South Florida | 2 | 2 | 0 | 0 | 1.00 |
| 10 | Navy | 4 | 2 | 0 | 0 | 0.50 |