2021 American Athletic Conference Leaders Interceptions - Games in November Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Houston | 4 | 7 | 74 | 0 | 1.75 |
| 2 | South Florida | 4 | 2 | 61 | 0 | 0.50 |
| 3 | Temple | 4 | 2 | 52 | 0 | 0.50 |
| 4 | Tulane | 4 | 4 | 49 | 0 | 1.00 |
| 5 | Memphis | 4 | 7 | 40 | 0 | 1.75 |
| 6 | UCF | 4 | 4 | 33 | 0 | 1.00 |
| 7 | SMU | 4 | 3 | 19 | 0 | 0.75 |
| 8 | Tulsa | 4 | 4 | 16 | 0 | 1.00 |
| 9 | Cincinnati | 4 | 3 | 11 | 0 | 0.75 |
| 10 | East Carolina | 4 | 3 | 2 | 0 | 0.75 |