2021 American Athletic Conference Leaders Passes Defended - Games vs. FCS (I-AA) Teams Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | East Carolina | 1 | 1 | 12 | 13 | 13.00 |
| 2 | UCF | 1 | 1 | 8 | 9 | 9.00 |
| 3 | Cincinnati | 1 | 3 | 4 | 7 | 7.00 |
| 3 | SMU | 1 | 3 | 4 | 7 | 7.00 |
| 5 | Memphis | 1 | 1 | 5 | 6 | 6.00 |
| 6 | South Florida | 1 | 0 | 5 | 5 | 5.00 |
| 6 | Tulsa | 1 | 0 | 5 | 5 | 5.00 |
| 8 | Tulane | 1 | 2 | 2 | 4 | 4.00 |
| 9 | Temple | 1 | 1 | 1 | 2 | 2.00 |
| 9 | Houston | 1 | 0 | 2 | 2 | 2.00 |