2021 American Athletic Conference Leaders Rushing Defense - In The 2nd Half/Overtime through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Houston | 14 | 220 | 690 | 3.14 | 7 | 44 | 38 | 22 | 6 |
| 2 | Navy | 12 | 185 | 750 | 4.05 | 13 | 43 | 42 | 30 | 5 |
| 3 | Tulane | 12 | 243 | 835 | 3.44 | 12 | 35 | 51 | 24 | 6 |
| 4 | UCF | 13 | 216 | 895 | 4.14 | 8 | 47 | 46 | 30 | 9 |
| 5 | SMU | 12 | 247 | 946 | 3.83 | 9 | 58 | 49 | 29 | 8 |
| 6 | Tulsa | 13 | 219 | 971 | 4.43 | 8 | 54 | 50 | 33 | 9 |
| 7 | Memphis | 12 | 249 | 1076 | 4.32 | 12 | 57 | 56 | 30 | 11 |
| 8 | East Carolina | 12 | 196 | 1087 | 5.55 | 13 | 90 | 51 | 33 | 13 |
| 9 | Cincinnati | 14 | 294 | 1098 | 3.73 | 9 | 37 | 61 | 35 | 5 |
| 10 | South Florida | 12 | 226 | 1390 | 6.15 | 14 | 97 | 62 | 39 | 12 |
| 11 | Temple | 12 | 269 | 1461 | 5.43 | 19 | 75 | 72 | 41 | 15 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||