2021 American Athletic Conference Leaders Rushing Defense - On 3rd Down through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | East Carolina | 12 | 74 | 83 | 1.12 | 3 | 26 | 21 | 4 | 1 |
| 2 | Houston | 14 | 84 | 144 | 1.71 | 2 | 39 | 22 | 8 | 2 |
| 3 | Navy | 12 | 70 | 153 | 2.19 | 3 | 15 | 25 | 5 | 0 |
| 4 | Tulane | 12 | 77 | 207 | 2.69 | 4 | 35 | 23 | 10 | 2 |
| 5 | Tulsa | 13 | 79 | 233 | 2.95 | 3 | 17 | 33 | 6 | 0 |
| 6 | UCF | 12 | 79 | 280 | 3.54 | 5 | 47 | 31 | 13 | 2 |
| 7 | SMU | 12 | 86 | 297 | 3.45 | 3 | 23 | 32 | 11 | 4 |
| 8 | Memphis | 12 | 87 | 319 | 3.67 | 3 | 36 | 44 | 12 | 2 |
| 9 | Temple | 12 | 84 | 331 | 3.94 | 3 | 58 | 36 | 10 | 3 |
| 10 | Cincinnati | 14 | 98 | 338 | 3.45 | 1 | 47 | 34 | 13 | 3 |
| 11 | South Florida | 12 | 59 | 409 | 6.93 | 3 | 42 | 24 | 10 | 5 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||