2021 American Athletic Conference Leaders Rushing Defense - On 4th Down through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 11 | 19 | -2 | -0.11 | 0 | 7 | 12 | 0 | 0 |
| 2 | UCF | 9 | 18 | 6 | 0.33 | 1 | 8 | 8 | 0 | 0 |
| 3 | Tulsa | 6 | 10 | 21 | 2.10 | 0 | 15 | 4 | 1 | 0 |
| 4 | Houston | 7 | 11 | 22 | 2.00 | 0 | 16 | 6 | 2 | 0 |
| 5 | Memphis | 9 | 16 | 29 | 1.81 | 2 | 9 | 10 | 0 | 0 |
| 6 | Navy | 7 | 10 | 42 | 4.20 | 0 | 17 | 6 | 2 | 0 |
| 7 | South Florida | 6 | 12 | 59 | 4.92 | 3 | 46 | 7 | 1 | 1 |
| 8 | East Carolina | 5 | 8 | 67 | 8.38 | 1 | 24 | 6 | 2 | 1 |
| 9 | SMU | 8 | 12 | 70 | 5.83 | 2 | 40 | 4 | 3 | 1 |
| 10 | Tulane | 10 | 20 | 106 | 5.30 | 2 | 32 | 15 | 2 | 2 |
| 11 | Temple | 8 | 17 | 132 | 7.76 | 1 | 50 | 14 | 3 | 3 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||