2021 American Athletic Conference Leaders Rushing Defense - In The 2nd Quarter through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | SMU | 12 | 99 | 292 | 2.95 | 2 | 40 | 18 | 11 | 3 |
| 2 | Houston | 14 | 122 | 348 | 2.85 | 3 | 41 | 18 | 10 | 2 |
| 3 | Tulane | 12 | 105 | 382 | 3.64 | 3 | 37 | 19 | 15 | 6 |
| 4 | Navy | 12 | 111 | 410 | 3.69 | 6 | 78 | 24 | 13 | 1 |
| 5 | East Carolina | 12 | 102 | 415 | 4.07 | 5 | 47 | 20 | 13 | 7 |
| 6 | Cincinnati | 14 | 138 | 448 | 3.25 | 3 | 51 | 28 | 11 | 3 |
| 7 | Tulsa | 13 | 134 | 464 | 3.46 | 7 | 64 | 23 | 11 | 3 |
| 8 | Memphis | 12 | 117 | 489 | 4.18 | 6 | 36 | 34 | 19 | 2 |
| 9 | UCF | 13 | 124 | 507 | 4.09 | 7 | 79 | 28 | 17 | 4 |
| 10 | South Florida | 12 | 104 | 572 | 5.50 | 7 | 33 | 31 | 24 | 9 |
| 11 | Temple | 12 | 145 | 581 | 4.01 | 7 | 47 | 33 | 20 | 4 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||